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MYO9B anticorps

MYO9B Reactivité: Humain, Souris, Rat WB, ELISA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7116615
  • Antigène Voir toutes MYO9B Anticorps
    MYO9B (Myosin IXB (MYO9B))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 11
    • 1
    Lapin
    Clonalité
    • 12
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYO9B est non-conjugé
    Application
    • 5
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    myosin IXB
    Isotype
    IgG
    Top Product
    Discover our top product MYO9B Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IP: 1:200-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    MYO9B (Myosin IXB (MYO9B))
    Autre désignation
    MYO9B (MYO9B Produits)
    Synonymes
    anticorps CELIAC4, anticorps MYR5, anticorps MYO9B, anticorps fb53f01, anticorps wu:fb53f01, anticorps wu:fc47c07, anticorps si:dkeyp-66d1.8, anticorps myosin IXB, anticorps myosin IXb, anticorps unconventional myosin-IXb, anticorps MYO9B, anticorps Myo9b, anticorps myo9b, anticorps LOC100450445
    Sujet
    Synonyms:MYR5 Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257).
    Poids moléculaire
    230-250kd
    ID gène
    4650
    UniProt
    Q13459
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