NDC80 anticorps

N° du produit ABIN7116759

Détail du produit anti-NDC80 anticorps

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDC80 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: NDC80 homolog, kinetochore complex component(S. cerevisiae)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur NDC80

Antigène: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Autre désignation: NDC80 (NDC80 Produits)

Synonymes: anticorps CG9938, anticorps Dmel\\CG9938, anticorps Hec1, anticorps NDC80, anticorps dNdc80, anticorps dmNdc80, anticorps hec1, anticorps KNTC2, anticorps ndc10, anticorps tid3, anticorps 2610020P18Rik, anticorps AV139730, anticorps HEC, anticorps HEC1, anticorps Kntc2, anticorps kntc2l, anticorps wu:fb52e02, anticorps zgc:111801, anticorps HsHec1, anticorps TID3, anticorps hsNDC80, anticorps kntc2, anticorps NDC80, kinetochore complex component, anticorps CG9938 gene product from transcript CG9938-RA, anticorps spindle pole body protein Ndc80, anticorps kinetochore protein Ndc80, anticorps NDC80 homolog, kinetochore complex component (S. cerevisiae), anticorps NDC80 kinetochore complex component, anticorps NDC80 kinetochore complex component S homeolog, anticorps NDC80, anticorps Ndc80, anticorps ndc80, anticorps ndc80.S

Sujet: Synonyms:HEC, HEC1, KNTC2 Background:Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).

Poids moléculaire: 76 kDa

ID gène: 10403

UniProt: O14777

Pathways: Maintenance of Protein Location