OSBPL3 anticorps

N° du produit ABIN7117176

Détail du produit anti-OSBPL3 anticorps

Antigène: OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OSBPL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: oxysterol binding protein-like 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur OSBPL3

Antigène: OSBPL3 (Oxysterol Binding Protein-Like 3 (OSBPL3))

Autre désignation: OSBPL3 (OSBPL3 Produits)

Synonymes: anticorps osbpl3, anticorps zgc:101089, anticorps OSBPL3, anticorps ORP-3, anticorps ORP3, anticorps OSBP3, anticorps 1200014M06Rik, anticorps 6720421I08Rik, anticorps A530055M08, anticorps RGD1564287, anticorps oxysterol binding protein like 3, anticorps oxysterol binding protein-like 3a, anticorps oxysterol binding protein-like 3, anticorps OSBPL3, anticorps osbpl3a, anticorps osbpl3, anticorps Osbpl3

Sujet: Synonyms:KIAA0704, ORP3, OSBP3 Background:Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193).

Poids moléculaire: 101 kDa

ID gène: 26031

UniProt: Q9H4L5