PASK anticorps

N° du produit ABIN7117245

Détail du produit anti-PASK anticorps

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PASK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: PAS domain containing serine/threonine kinase

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur PASK

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Autre désignation: PASK (PASK Produits)

Synonymes: anticorps pas, anticorps wu:fb69h07, anticorps PASK, anticorps PASKIN, anticorps STK37, anticorps mKIAA0135, anticorps PAS domain containing serine/threonine kinase, anticorps Pask, anticorps pask, anticorps PASK

Sujet: Synonyms:KIAA0135 Background:Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions(oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Poids moléculaire: 180 kDa

ID gène: 23178

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process