PDE12 anticorps
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- Antigène Voir toutes PDE12 Anticorps
- PDE12 (Phosphodiesterase 12 (PDE12))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PDE12 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- phosphodiesterase 12
- Isotype
- IgG
- Top Product
- Discover our top product PDE12 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- PDE12 (Phosphodiesterase 12 (PDE12))
- Autre désignation
- PDE12 (PDE12 Produits)
- Synonymes
- anticorps 2'-PDE, anticorps E430028B21Rik, anticorps LRRGT00074, anticorps RGD1310975, anticorps phosphodiesterase 12 S homeolog, anticorps phosphodiesterase 12, anticorps pde12.S, anticorps PDE12, anticorps pde12, anticorps Pde12
- Sujet
- Synonyms: Background:Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons(IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
- Poids moléculaire
- 65kd
- ID gène
- 201626
- UniProt
- Q6L8Q7
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