PDE9A anticorps

N° du produit ABIN7117437

Détail du produit anti-PDE9A anticorps

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE9A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: phosphodiesterase 9A

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:100-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur PDE9A

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Autre désignation: PDE9A (PDE9A Produits)

Synonymes: anticorps PDE9A, anticorps MGC116558, anticorps Pde9a, anticorps HSPDE9A2, anticorps PDE9A1, anticorps phosphodiesterase 9A, anticorps phosphodiesterase 9A S homeolog, anticorps high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, anticorps PDE9A, anticorps pde9a.S, anticorps Pde9a, anticorps LOC100549810, anticorps pde9a

Sujet: Synonyms:HSPDE9A2, PDE9A, phosphodiesterase 9A Background:Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).

ID gène: 5152

UniProt: O76083