KCNAB1 anticorps
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- Antigène Voir toutes KCNAB1 Anticorps
- KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KCNAB1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- potassium voltage-gated channel, shaker-related subfamily, beta member 1
- Isotype
- IgG
- Top Product
- Discover our top product KCNAB1 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- KCNAB1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 1 (KCNAB1))
- Autre désignation
- KCNAB1 (KCNAB1 Produits)
- Synonymes
- anticorps KCNAB1, anticorps zgc:113627, anticorps AKR6A3, anticorps KCNA1B, anticorps KV-BETA-1, anticorps Kvb1.3, anticorps hKvBeta3, anticorps hKvb3, anticorps Kvbeta1.1, anticorps KVBETA1, anticorps Kv-beta-1, anticorps Akr8a8, anticorps mKv(beta)1, anticorps KvBeta3, anticorps potassium voltage-gated channel subfamily A member regulatory beta subunit 1, anticorps potassium voltage-gated channel, shaker-related subfamily, beta member 1 a, anticorps potassium voltage-gated channel, shaker-related subfamily, beta member 1, anticorps KCNAB1, anticorps kcnab1a, anticorps Kcnab1
- Sujet
- Synonyms:KCNA1B Background:Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits(PubMed:7499366, PubMed:7603988, PubMed:17156368,PubMed:17540341, PubMed:19713757). Modulates action potentials via its effect on the pore-forming alpha subunits(By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity(By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members(PubMed:9763623). Promotes the closure of KCNA1, KCNA2 and KCNA5 channels(PubMed:7499366, PubMed:7890032, PubMed:7603988, PubMed:7649300, PubMed:8938711, PubMed:12077175, PubMed:12130714, PubMed:15361858, PubMed:17540341, PubMed:19713757). Accelerates KCNA4 channel closure(PubMed:7890032, PubMed:7649300, PubMed:7890764, PubMed:9763623). Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4(PubMed:17156368). Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6(By similarity). Isoform KvB1.2 has no effect on KCNA1, KCNA2 or KCNB1(PubMed:7890032, PubMed:7890764). Enhances KCNB1 and KCNB2 channel activity(By similarity). Binds NADPH, this is required for efficient down-regulation of potassium channel activity(PubMed:17540341). Has NADPH-dependent aldoketoreductase activity(By similarity). Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity(By similarity).
- Poids moléculaire
- 68 kDa
- ID gène
- 7881
- UniProt
- Q14722
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