PPP1CC anticorps

N° du produit ABIN7117989

Détail du produit anti-PPP1CC anticorps

Antigène: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1CC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: protein phosphatase 1, catalytic subunit, gamma isoform

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur PPP1CC

Antigène: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Autre désignation: PPP1CC (PPP1CC Produits)

Synonymes: anticorps PP-1G, anticorps ppp1g, anticorps PP1, anticorps dis2m1, anticorps fe06g11, anticorps fi22e08, anticorps wu:fe06g11, anticorps wu:fi22e08, anticorps PP1C, anticorps PPP1G, anticorps Ppp1cc1, anticorps ppp1cc-a, anticorps protein phosphatase 1, catalytic subunit, gamma isozyme, anticorps protein phosphatase 1, catalytic subunit, gamma isoform, anticorps protein phosphatase 1 catalytic subunit gamma, anticorps protein phosphatase 1, catalytic subunit, gamma isozyme L homeolog, anticorps ppp1cc, anticorps Ppp1cc, anticorps PPP1CC, anticorps ppp1cc.L

Sujet: Synonyms: Background:Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1(PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells(Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective(PubMed:23396208).

Poids moléculaire: 35 kDa

ID gène: 5501

UniProt: P36873

Pathways: Cellular Glucan Metabolic Process, Lipid Metabolism