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PPP1R9B anticorps

PPP1R9B Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7118007
  • Antigène Voir toutes PPP1R9B Anticorps
    PPP1R9B (Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B))
    Reactivité
    Humain, Rat, Souris
    Hôte
    • 44
    • 1
    • 1
    Lapin
    Clonalité
    • 46
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PPP1R9B est non-conjugé
    Application
    • 38
    • 20
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    protein phosphatase 1, regulatory(inhibitor) subunit 9B
    Isotype
    IgG
    Top Product
    Discover our top product PPP1R9B Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    PPP1R9B (Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B))
    Autre désignation
    PPP1R9B (PPP1R9B Produits)
    Synonymes
    anticorps Neb2, anticorps PPP1R6, anticorps PPP1R9, anticorps SPINO, anticorps Spn, anticorps SPL, anticorps protein phosphatase 1, regulatory subunit 9B, anticorps protein phosphatase 1 regulatory subunit 9B, anticorps Ppp1r9b, anticorps PPP1R9B
    Sujet
    Synonyms:PPP1R6 Background:Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments(F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1(By similarity). Required for hepatocyte growth factor(HGF)-induced cell migration.
    Poids moléculaire
    120-130 kDa
    ID gène
    84687
    UniProt
    Q96SB3
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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