RSAD2 anticorps
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- Antigène Voir toutes RSAD2 Anticorps
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RSAD2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- radical S-adenosyl methionine domain containing 2
- Isotype
- IgG
- Top Product
- Discover our top product RSAD2 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- Autre désignation
- RSAD2 (RSAD2 Produits)
- Synonymes
- anticorps CIG6, anticorps RSAD2, anticorps 2510004L01Rik, anticorps cig33, anticorps cig5, anticorps vig1, anticorps Vig1, anticorps Best5, anticorps si:ch211-276e8.2, anticorps zgc:112342, anticorps viperin, anticorps rsad2, anticorps radical S-adenosyl methionine domain containing 2, anticorps viperin, anticorps RSAD2, anticorps Rsad2, anticorps rsad2, anticorps vig1
- Sujet
- Synonyms:2510004L01Rik, cig33, cig5, RSAD2, vig1, Viperin Background:Interferon-inducible iron-sulfur(4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus(HCMV), hepatitis C virus(HCV), west Nile virus(WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus(VSV), and human immunodeficiency virus(HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase(FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells(pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor(TCR)-mediated GATA3 activation and optimal T-helper 2(Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
- Poids moléculaire
- 45 kDa
- ID gène
- 91543
- UniProt
- Q8WXG1
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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