RPRD1B anticorps
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- Antigène Voir toutes RPRD1B Anticorps
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RPRD1B est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- regulation of nuclear pre-mRNA domain containing 1B
- Isotype
- IgG
- Top Product
- Discover our top product RPRD1B Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
- Autre désignation
- RPRD1B (RPRD1B Produits)
- Synonymes
- anticorps fb23h08, anticorps zgc:55687, anticorps wu:fb23h08, anticorps rprd1ba, anticorps MGC130705, anticorps C13H20ORF77, anticorps C20orf77, anticorps CREPT, anticorps NET60, anticorps dJ1057B20.2, anticorps 2610304G08Rik, anticorps 2810446G03Rik, anticorps Crept, anticorps RGD1304782, anticorps regulation of nuclear pre-mRNA domain containing 1B, anticorps regulation of nuclear pre-mRNA domain containing 1B L homeolog, anticorps rprd1b, anticorps rprd1b.L, anticorps RPRD1B, anticorps Rprd1b
- Sujet
- Synonyms:C20orf77, CREPT Background:Interacts with phosphorylated C-terminal heptapeptide repeat domain(CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
- Poids moléculaire
- 37 kDa
- ID gène
- 58490
- UniProt
- Q9NQG5
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