anticorps RGS17, anticorps zgc:92802, anticorps MGC179306, anticorps RGS-17, anticorps RGSZ2, anticorps hRGS17, anticorps 6430507P11Rik, anticorps Rgsz2, anticorps regulator of G protein signaling 17, anticorps regulator of G-protein signaling 17, anticorps RGS17, anticorps Rgs17, anticorps rgs17
Sujet
Synonyms:RGSZ2 Background:Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins(By similarity).