RHBDD1 anticorps

N° du produit ABIN7118505

Détail du produit anti-RHBDD1 anticorps

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: rhomboid domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RHBDD1 (RHBDD1 Produits)

Synonymes: anticorps MGC84665, anticorps RRP4, anticorps 4930418P06Rik, anticorps mRHBDD1, anticorps RGD1306477, anticorps rRHBDD1, anticorps rhomboid domain containing 1, anticorps rhomboid domain containing 1 L homeolog, anticorps RHBDD1, anticorps rhbdd1.L, anticorps rhbdd1, anticorps Rhbdd1

Sujet: Synonyms:RHBDL4 Background:Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation(ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum(ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.

Poids moléculaire: 36 kDa

ID gène: 84236

UniProt: Q8TEB9