anticorps AA516740, anticorps BC035291, anticorps KMT2G, anticorps mKIAA1076, anticorps Set1B, anticorps im:7156157, anticorps si:dkey-237o15.4, anticorps setd1b, anticorps SET domain containing 1B, anticorps SET domain containing 1B, a, anticorps SET domain containing 1B S homeolog, anticorps Setd1b, anticorps SETD1B, anticorps setd1ba, anticorps setd1b.S
Sujet
Synonyms:KIAA1076, KMT2G, SET1B Background:Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro.