SRGAP2 anticorps

N° du produit ABIN7119134

Détail du produit anti-SRGAP2 anticorps

Antigène: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRGAP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: SLIT-ROBO Rho GTPase activating protein 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SRGAP2

Antigène: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Autre désignation: SRGAP2 (SRGAP2 Produits)

Synonymes: anticorps ARHGAP34, anticorps FNBP2, anticorps SRGAP2A, anticorps SRGAP3, anticorps 9930124L22Rik, anticorps AI448945, anticorps FBP2, anticorps Fnbp2, anticorps srGAP3, anticorps AI452337, anticorps Arhgap14, anticorps D130026O08Rik, anticorps Gbi, anticorps MEGAP, anticorps WRP, anticorps mKIAA0411, anticorps RGD1566016, anticorps srGAP2, anticorps srgap2a, anticorps wu:fb47h12, anticorps zgc:136814, anticorps fnbp2, anticorps srgap2, anticorps SLIT-ROBO Rho GTPase activating protein 2, anticorps SLIT-ROBO Rho GTPase activating protein 3, anticorps SLIT-ROBO Rho GTPase activating protein 2 L homeolog, anticorps SRGAP2, anticorps Srgap2, anticorps Srgap3, anticorps srgap2, anticorps srgap2.L

Sujet: Synonyms:ARHGAP34, FNBP2, Formin binding protein 2, KIAA0456, SRGAP2, srGAP3 Background:RAC1 GTPase activating protein(GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.

Poids moléculaire: 130 kDa

ID gène: 23380

UniProt: O75044