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SNAPIN anticorps

SNAPIN Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IP, IF, FACS Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7119201
  • Antigène Voir toutes SNAPIN Anticorps
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    Reactivité
    • 34
    • 3
    • 3
    • 1
    Humain, Souris, Rat
    Hôte
    • 26
    • 8
    • 1
    Lapin
    Clonalité
    • 30
    • 5
    Polyclonal
    Conjugué
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SNAPIN est non-conjugé
    Application
    • 13
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    SNAP-associated protein
    Isotype
    IgG
    Top Product
    Discover our top product SNAPIN Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    SNAPIN (SNAP-Associated Protein (SNAPIN))
    Autre désignation
    SNAPIN (SNAPIN Produits)
    Synonymes
    anticorps SNAPAP, anticorps si:dkey-222b8.2, anticorps SNAPIN, anticorps BLOC1S7, anticorps BLOS7, anticorps 25kDa, anticorps AA407989, anticorps AV026596, anticorps Bloc1s7, anticorps Snap25bp, anticorps Snapap, anticorps SNAP associated protein, anticorps SNAP-associated protein L homeolog, anticorps SNAP-associated protein, anticorps SNAPIN, anticorps snapin.L, anticorps snapin, anticorps Snapin
    Sujet
    Synonyms:BLOC1S7, SNAP25BP, SNAPAP Background:Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles(LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells(PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor(PubMed:25898167).
    Poids moléculaire
    15-18 kDa
    ID gène
    23557
    UniProt
    O95295
    Pathways
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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