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SLC5A8 anticorps

SLC5A8 Reactivité: Humain, Souris, Rat WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7119316
  • Antigène Voir toutes SLC5A8 Anticorps
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    Reactivité
    • 32
    • 32
    • 22
    • 4
    • 4
    • 4
    • 1
    Humain, Souris, Rat
    Hôte
    • 49
    Lapin
    Clonalité
    • 49
    Polyclonal
    Conjugué
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC5A8 est non-conjugé
    Application
    • 38
    • 20
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    solute carrier family 5(iodide transporter), member 8
    Isotype
    IgG
    Top Product
    Discover our top product SLC5A8 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
    Autre désignation
    SLC5A8 (SLC5A8 Produits)
    Synonymes
    anticorps Ait, anticorps SMCT, anticorps SMCT1, anticorps AIT, anticorps RGD1564146, anticorps solute carrier family 5 (iodide transporter), member 8, anticorps solute carrier family 5 member 8, anticorps Slc5a8, anticorps SLC5A8
    Sujet
    Synonyms:AIT, Background:Acts as an electrogenic sodium(Na(+)) and chloride(Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates(short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs(nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies(beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
    Poids moléculaire
    67 kDa
    ID gène
    160728
    UniProt
    Q8N695
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