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SMC5 anticorps

SMC5 Reactivité: Humain, Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7119560
  • Antigène Voir toutes SMC5 Anticorps
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Reactivité
    • 34
    • 17
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 32
    • 1
    • 1
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMC5 est non-conjugé
    Application
    • 22
    • 13
    • 13
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    structural maintenance of chromosomes 5
    Isotype
    IgG
    Top Product
    Discover our top product SMC5 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Autre désignation
    SMC5 (SMC5 Produits)
    Synonymes
    anticorps F1N13.60, anticorps F1N13_60, anticorps structural maintenance of chromosomes 5, anticorps SMC-5, anticorps SMC5L1, anticorps MLZ-453, anticorps Smc5l1, anticorps mKIAA0594, anticorps mSMC5, anticorps structural maintenance of chromosomes 5, anticorps structural maintenance of chromosomes 5 S homeolog, anticorps SMC5, anticorps smc5, anticorps Smc5, anticorps smc5.S
    Sujet
    Synonyms:KIAA0594, SMC5L1 Background:Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT(alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex(telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies(APBs). Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome(PubMed:26983541).
    Poids moléculaire
    120-130 kDa
    ID gène
    23137
    UniProt
    Q8IY18
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