SENP3 anticorps

N° du produit ABIN7119591

Détail du produit anti-SENP3 anticorps

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: SUMO1/sentrin/SMT3 specific peptidase 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SENP3

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Autre désignation: SENP3 (SENP3 Produits)

Synonymes: anticorps SMT3IP1, anticorps SSP3, anticorps Ulp1, anticorps AA408656, anticorps Smt3ip, anticorps Smt3ip1, anticorps ssp3, anticorps smt3ip1, anticorps fa03d07, anticorps wu:fa03d07, anticorps senp3, anticorps SUMO1/sentrin/SMT3 specific peptidase 3, anticorps SUMO/sentrin specific peptidase 3, anticorps Sumo1/sentrin/SMT3 specific peptidase 3, anticorps SUMO1/sentrin/SMT3 specific peptidase 3b, anticorps SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog, anticorps SENP3, anticorps Senp3, anticorps senp3, anticorps senp3b, anticorps senp3.L

Sujet: Synonyms:SSP3, SUSP3 Background:Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Poids moléculaire: 65-70 kDa

ID gène: 26168

UniProt: Q9H4L4