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TBC1D5 anticorps

TBC1D5 Reactivité: Humain, Souris, Rat WB, ELISA, IP, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7119805
  • Antigène Voir toutes TBC1D5 Anticorps
    TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 3
    Lapin
    Clonalité
    • 3
    Polyclonal
    Conjugué
    • 3
    Cet anticorp TBC1D5 est non-conjugé
    Application
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    TBC1 domain family, member 5
    Isotype
    IgG
    Top Product
    Discover our top product TBC1D5 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2400, IP: 1:200-1:1000 , IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
    Autre désignation
    TBC1D5 (TBC1D5 Produits)
    Synonymes
    anticorps RGD1561626, anticorps 1600014N05Rik, anticorps mKIAA0210, anticorps TBC1 domain family, member 5, anticorps TBC1 domain family member 5, anticorps Tbc1d5, anticorps TBC1D5
    Sujet
    Synonyms:KIAA0210 Background:May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN), the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492).
    Poids moléculaire
    89 kDa
    ID gène
    9779
    UniProt
    Q92609
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