TEAD2 anticorps
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- Antigène Voir toutes TEAD2 Anticorps
- TEAD2 (TEA Domain Family Member 2 (TEAD2))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TEAD2 est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- TEA domain family member 2
- Isotype
- IgG
- Top Product
- Discover our top product TEAD2 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- TEAD2 (TEA Domain Family Member 2 (TEAD2))
- Autre désignation
- TEAD2 (TEAD2 Produits)
- Synonymes
- anticorps TEAD2, anticorps ETF, anticorps TEAD-2, anticorps TEF-4, anticorps TEF4, anticorps Etdf, anticorps TEA domain transcription factor 2, anticorps TEA domain family member 2, anticorps TEAD2, anticorps Tead2
- Sujet
- Synonyms:TEF4 Background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds to the SPH and GT-IIC 'enhansons'(5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
- Poids moléculaire
- 55-65 kDa
- ID gène
- 8463
- UniProt
- Q15562
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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