TELO2 anticorps

N° du produit ABIN7119824

Détail du produit anti-TELO2 anticorps

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TELO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: TEL2, telomere maintenance 2, homolog(S. cerevisiae)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur TELO2

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Autre désignation: TELO2 (TELO2 Produits)

Synonymes: anticorps RGD1305553, anticorps 1200003M09Rik, anticorps AI415602, anticorps Tel2, anticorps mKIAA0683, anticorps CLK2, anticorps TEL2, anticorps telomere maintenance 2, anticorps Telo2, anticorps TELO2

Sujet: Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

Poids moléculaire: 92 kDa

ID gène: 9894

UniProt: Q9Y4R8