TEX14 anticorps

N° du produit ABIN7119846

Détail du produit anti-TEX14 anticorps

Antigène: TEX14 (Testis Expressed 14 (TEX14))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEX14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: testis expressed 14

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur TEX14

Antigène: TEX14 (Testis Expressed 14 (TEX14))

Autre désignation: TEX14 (TEX14 Produits)

Synonymes: anticorps CT113, anticorps C85585, anticorps testis expressed 14, intercellular bridge forming factor, anticorps testis expressed gene 14, anticorps inactive serine/threonine-protein kinase TEX14, anticorps TEX14, anticorps Tex14, anticorps tex14, anticorps LOC100389169

Sujet: Synonyms:SGK307 Background:Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).

Poids moléculaire: 180-200 kDa, 106 kDa

ID gène: 56155

UniProt: Q8IWB6

Pathways: Maintenance of Protein Location