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TMED2 anticorps

TMED2 Reactivité: Humain, Souris ELISA, WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7120178
  • Antigène Voir toutes TMED2 Anticorps
    TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))
    Reactivité
    • 37
    • 15
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 37
    Lapin
    Clonalité
    • 37
    Polyclonal
    Conjugué
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TMED2 est non-conjugé
    Application
    • 25
    • 19
    • 17
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    transmembrane emp24 domain trafficking protein 2
    Isotype
    IgG
    Top Product
    Discover our top product TMED2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))
    Autre désignation
    TMED2 (TMED2 Produits)
    Synonymes
    anticorps P24A, anticorps RNP24, anticorps p24, anticorps 1110032D12Rik, anticorps 1810020N21Rik, anticorps Rnp24, anticorps Sid394, anticorps p24beta1, anticorps Chop24, anticorps transmembrane p24 trafficking protein 2, anticorps TMED2, anticorps Tmed2
    Sujet
    Synonyms:RNP24 Background:Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor, the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors(GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
    Poids moléculaire
    23 kDa
    ID gène
    10959
    UniProt
    Q15363
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