TNPO2 anticorps

N° du produit ABIN7120247

Détail du produit anti-TNPO2 anticorps

Antigène: TNPO2 (Transportin 2 (TNPO2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNPO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transportin 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur TNPO2

Antigène: TNPO2 (Transportin 2 (TNPO2))

Autre désignation: TNPO2 (TNPO2 Produits)

Synonymes: anticorps TNPO2, anticorps IPO3, anticorps KPNB2B, anticorps TRN2, anticorps ik:tdsubc_2a7, anticorps tdsubc_2a7, anticorps wu:fb01c02, anticorps wu:fe01f03, anticorps wu:fe16e12, anticorps xx:tdsubc_2a7, anticorps zgc:101009, anticorps 1110034O24Rik, anticorps AA414969, anticorps AI464345, anticorps AI852433, anticorps Knpb2b, anticorps Kpnb2b, anticorps transportin 2, anticorps transportin 2 L homeolog, anticorps transportin 2 (importin 3, karyopherin beta 2b), anticorps TNPO2, anticorps tnpo2.L, anticorps Tnpo2, anticorps tnpo2

Sujet: Synonyms: Background:Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity).

Poids moléculaire: 90-100 kDa

ID gène: 30000

UniProt: O14787