Tubulin anticorps (acLys40)

N° du produit ABIN7120355

Détail du produit anti-Tubulin anticorps

Antigène: Tubulin (TUB)

Épitope: acLys40

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tubulin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: tubulin, alpha 1a

Clone: 6A10

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:5000, IF: 1:20-1:200, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur Tubulin

Antigène: Tubulin (TUB)

Autre désignation: tubulin (TUB Produits)

Synonymes: anticorps 4t, anticorps B4t, anticorps BETA 98B, anticorps CG4869, anticorps DTB1, anticorps Dmbeta4, anticorps Dmel\\CG4869, anticorps T, anticorps Tub, anticorps beta-Tub, anticorps beta-Tub97EF, anticorps beta-tub, anticorps beta4, anticorps beta4t, anticorps beta97F, anticorps betaTub4, anticorps betaTub98BC, anticorps betaTub98C, anticorps beta-Tubulin at 97EF, anticorps betaTub97EF

Sujet: Synonyms:Acetylated alpha tubulin, Acetylated tubulin, acetylated-a-tubulin, acetyl-a-tubulin, alpha tubulin, Alpha tubulin 3, tubulin,TUBA1A Background:Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin, it does not recognize non-acetylated tubulin.

Poids moléculaire: 52 kDa

ID gène: 7846

UniProt: Q71U36