USP37 anticorps

N° du produit ABIN7120518

Détail du produit anti-USP37 anticorps

Antigène: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP37 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 37

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur USP37

Antigène: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Autre désignation: USP37 (USP37 Produits)

Synonymes: anticorps 4932415L06Rik, anticorps C330008N13Rik, anticorps wu:fi15b04, anticorps wu:fi38d03, anticorps zgc:152882, anticorps zgc:153999, anticorps ubiquitin specific peptidase 37, anticorps USP37, anticorps usp37, anticorps Usp37

Sujet: Synonyms:Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37 Background:Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).

Poids moléculaire: 110 kDa,70 kDa

ID gène: 57695

UniProt: Q86T82