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VPS41 anticorps

VPS41 Reactivité: Humain ELISA, WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7120712
  • Antigène Voir toutes VPS41 Anticorps
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    Reactivité
    • 16
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 14
    • 1
    • 1
    Lapin
    Clonalité
    • 16
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp VPS41 est non-conjugé
    Application
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    vacuolar protein sorting 41 homolog(S. cerevisiae)
    Isotype
    IgG
    Top Product
    Discover our top product VPS41 Anticorps primaire
  • Indications d'application
    WB: 1:200-1:1000, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
    Autre désignation
    VPS41 (VPS41 Produits)
    Synonymes
    anticorps AI317346, anticorps Vam2, anticorps mVam2, anticorps HVPS41, anticorps HVSP41, anticorps hVps41p, anticorps RGD1560511, anticorps ATVAM2, anticorps ATVPS41, anticorps T23G18.5, anticorps T23G18_5, anticorps VACUOLAR PROTEIN SORTING 41, anticorps VAM2, anticorps ZIGZAG SUPPRESSOR 2, anticorps ZIP2, anticorps vacuolar protein sorting 41, anticorps Vacuolar assembly protein VPS41 homolog, anticorps VPS41, HOPS complex subunit, anticorps vacuolar protein sorting 41, anticorps vacuolar protein sorting 41, putative, anticorps Vacuolar protein sorting-associated protein 41 homolog, anticorps VPS41 HOPS complex subunit, anticorps Bm1_34430, anticorps VPS41, anticorps CNI02550, anticorps CC1G_08871, anticorps MCYG_00680, anticorps VDBG_03430, anticorps MGYG_01292, anticorps CGB_H3560C, anticorps vps-41, anticorps Vps41
    Sujet
    Synonyms:HVPS41, hVps41p, HVSP41, S53, VPS41 Background:Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes(PubMed:23351085). Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo(PubMed:9159129, PubMed:23167963, PubMed:25445562, PubMed:25908847). Required for fusion of autophagosomes with lysosomes(PubMed:25783203). May link the HOPS complex to endosomal Rab7 via its association with RILP and to lysosomal membranes via its association with ARL8B, suggesting that these interactions may bring the compartments to close proximity for fusion(PubMed:25445562, PubMed:25908847). Involved in the direct trans-Golgi network to late endosomes transport of lysosomal membrane proteins independently of HOPS(PubMed:23322049). Involved in sorting to the regulated secretory pathway presumably implicating the AP-3 adaptor complex(By similarity). May play a role in HOPS-independent function in the regulated secretory pathway(PubMed:24210660).
    Poids moléculaire
    70 kDa, 93 kDa
    ID gène
    27072
    UniProt
    P49754
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