VEGF anticorps

N° du produit ABIN7120740

Détail du produit anti-VEGF anticorps

Antigène: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VEGF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: protein A+G purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: vascular endothelial growth factor A

Clone: 5H5

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:1000-1:4000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01MPBS pH 7.4,

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur VEGF

Antigène: VEGF (Vascular Endothelial Growth Factor (VEGF))

Autre désignation: VEGF (VEGF Produits)

Synonymes: anticorps MVCD1, anticorps VEGF, anticorps VPF, anticorps Vegf, anticorps Vegf120, anticorps Vegf164, anticorps Vegf188, anticorps Vpf, anticorps VEGF-A, anticorps VEGF164, anticorps eVEGF120, anticorps eVEGF164, anticorps vegf-a, anticorps vegf, anticorps vascular endothelial growth factor A, anticorps vascular endothelial growth factor A L homeolog, anticorps vascular endothelial growth factor, anticorps vascular endothelial growth factor precursor, anticorps VEGFA, anticorps Vegfa, anticorps vegfa.L, anticorps VEGF, anticorps vegf

Sujet: Synonyms:L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF Background:VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA.

Poids moléculaire: 45 kDa

UniProt: P15692