VAMP8 anticorps

N° du produit ABIN7120762

Détail du produit anti-VAMP8 anticorps

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAMP8 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: vesicle-associated membrane protein 8(endobrevin)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur VAMP8

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Autre désignation: VAMP8 (VAMP8 Produits)

Synonymes: anticorps vamp8, anticorps EDB, anticorps VAMP-8, anticorps AU041171, anticorps Edb, anticorps endobrevin, anticorps wu:fa18d07, anticorps zgc:56588, anticorps vesicle associated membrane protein 8, anticorps vesicle-associated membrane protein 8 (endobrevin), anticorps vesicle-associated membrane protein 8, anticorps vamp8, anticorps VAMP8, anticorps Vamp8

Sujet: Synonyms:EDB, Endobrevin, VAMP 8, VAMP8 Background:SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

Poids moléculaire: 15 kDa

ID gène: 8673

UniProt: Q9BV40