WDR1 anticorps

N° du produit ABIN7120810

Détail du produit anti-WDR1 anticorps

Antigène: WDR1 (WD Repeat Domain 1 (WDR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: WD repeat domain 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur WDR1

Antigène: WDR1 (WD Repeat Domain 1 (WDR1))

Autre désignation: WDR1 (WDR1 Produits)

Synonymes: anticorps AIP1, anticorps NORI-1, anticorps Aip1, anticorps D5Wsu185e, anticorps rede, anticorps aip1, anticorps wdr1b, anticorps wu:fa66e09, anticorps zgc:55793, anticorps zgc:77547, anticorps wdr1, anticorps wdr1-a, anticorps wdr1-b, anticorps wdr1a, anticorps xAIP1-B, anticorps WD repeat domain 1, anticorps WD repeat domain 1 L homeolog, anticorps WD repeat domain 1 S homeolog, anticorps WDR1, anticorps Wdr1, anticorps wdr1.L, anticorps wdr1, anticorps wdr1.S

Sujet: Synonyms:Actin interacting protein 1, AIP1, NORI 1, WD repeat containing protein 1, WD repeat domain 1, WDR1 Background:Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins(PubMed:15629458). Enhances cofilin-mediated actin severing(By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions(PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance(By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity(PCP) during follicular epithelium development and for cell shape changes during PCP, the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension(By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt(PubMed:25792565).

Poids moléculaire: 66 kDa

ID gène: 9948

UniProt: O75083

Pathways: Sensory Perception of Sound