WDR24 anticorps

N° du produit ABIN7120816

Détail du produit anti-WDR24 anticorps

Antigène: WDR24 (WD Repeat Domain 24 (WDR24))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR24 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: WD repeat domain 24

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur WDR24

Antigène: WDR24 (WD Repeat Domain 24 (WDR24))

Autre désignation: WDR24 (WDR24 Produits)

Synonymes: anticorps C16orf21, anticorps JFP7, anticorps BC037651, anticorps wu:fd05f12, anticorps zgc:55946, anticorps WD repeat domain 24, anticorps WD repeat domain 24 L homeolog, anticorps WDR24, anticorps Wdr24, anticorps wdr24, anticorps wdr24.L

Sujet: Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

Poids moléculaire: 102 kDa

ID gène: 84219

UniProt: Q96S15