ZNF238 anticorps

N° du produit ABIN7120963

Détail du produit anti-ZNF238 anticorps

Antigène: ZNF238 (Zinc Finger Protein 238 (ZNF238))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF238 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: zinc finger protein 238

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ZNF238

Antigène: ZNF238 (Zinc Finger Protein 238 (ZNF238))

Autre désignation: ZNF238 (ZNF238 Produits)

Synonymes: anticorps si:ch211-221n23.1, anticorps znf238, anticorps C2H2-171, anticorps RP58, anticorps TAZ-1, anticorps ZNF238, anticorps Zfp238, anticorps Znf238, anticorps Rp58, anticorps Zbtb18, anticorps zinc finger and BTB domain containing 18, anticorps zinc finger and BTB domain containing 18 L homeolog, anticorps zbtb18, anticorps zbtb18.L, anticorps ZBTB18, anticorps Zbtb18

Sujet: Synonyms:58 kDa repressor protein, C2H2 171, RP58, TAZ 1, TAZ1, Transcriptional repressor RP58, ZBTB18, ZFP238, zinc finger protein 238, Zinc finger protein C2H2 171, ZNF238 Background:ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60- kDa band which corresponds to the full length of RP58 protein. In addition, a 48- kDa band, thought to be the truncated form 2 is detected(PMID: 9756912).

Poids moléculaire: 48 kDa

UniProt: Q99592