Follistatin anticorps

N° du produit ABIN7504142

Détail du produit anti-Follistatin anticorps

Antigène: Follistatin (FST)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Follistatin est non-conjugé

Application: ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. FST/4281 is a clone raised against recombinant Fst 288, and is used in combination, commonly as the capture, with antibody FST/4282 in a two site ELISA for the detection of Follistatin.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Raised to human Follistatin (Fst) 288 and recognizes both human Fst 288 and 315

Isotype: IgG1

Information d'application

Indications d'application:

Positive Control: Human testis or ovary.

Known Application: ELISA (Use in combination with clone FST/4282 for two-site ELISA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur Follistatin

Antigène: Follistatin (FST)

Autre désignation: FST (FST Produits)

Synonymes: anticorps CG12955, anticorps CG12956, anticorps CG33466, anticorps Dmel\\CG33466, anticorps Fol1, anticorps dFS, anticorps dFol1, anticorps dfs, anticorps fs, anticorps FS, anticorps foll, anticorps xfs, anticorps FST, anticorps fst, anticorps AL033346, anticorps FOL1, anticorps Fst-288, anticorps RATFOL1, anticorps cb446, anticorps fd07h10, anticorps fst1, anticorps wu:fd07h10, anticorps Follistatin, anticorps follistatin, anticorps follistatin L homeolog, anticorps follistatin a, anticorps Fs, anticorps fst, anticorps FST, anticorps LOC100141662, anticorps fst.L, anticorps Fst, anticorps fsta

Sujet: Follistatin, FS, FST, Active-binding protein,Follistatin / Activin Binding Protein
Cellular localisation: Secreted.

Poids moléculaire: 37kDa

ID gène: 10468, 9914

UniProt: P19883

Pathways: Negative Regulation of Hormone Secretion