DMRT2 anticorps

N° du produit ABIN7504176

Détail du produit anti-DMRT2 anticorps

Antigène: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DMRT2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificité: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human DMRT2 protein

Isotype: IgG2b

Information d'application

Indications d'application:

Positive Control: HeLa or MCF-7 cells.

Known Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur DMRT2

Antigène: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Autre désignation: DMRT2 (DMRT2 Produits)

Synonymes: anticorps dmrt2, anticorps zDmrt2, anticorps Terra, anticorps DMRT2, anticorps dmrt2a, anticorps MGC131063, anticorps Terra-like, anticorps Ci-DMRT2, anticorps doublesex and mab-3 related transcription factor 2, anticorps doublesex and mab-3 related transcription factor 2a, anticorps doublesex and mab-3 related transcription factor 2 L homeolog, anticorps doublesex and mab-3 related transcription factor 2b, anticorps DMRT2, anticorps dmrt2a, anticorps Dmrt2, anticorps dmrt2, anticorps dmrt2.L, anticorps LOC778577, anticorps dmrt2b

Sujet: Doublesex and mab-3 related transcription factor 2, doublesex-like 2 protein (DSXL-2), terra like protein antibody,DMRT2 (Transcription Factor)
Cellular localisation: Nucleus

Poids moléculaire: 62kDa

ID gène: 10655, 59506

UniProt: Q9Y5R5