TDRKH anticorps

N° du produit ABIN7126210

Détail du produit anti-TDRKH anticorps

Antigène: TDRKH (Tudor and KH Domain Containing (TDRKH))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TDRKH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.

Réactivité croisée (Details): Human. Predicted to react with Mouse and Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human TDRKH protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or MCF7 cells. Human testis or brain.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TDRKH

Antigène: TDRKH (Tudor and KH Domain Containing (TDRKH))

Autre désignation: TDRKH (TDRKH Produits)

Synonymes: anticorps RGD1311196, anticorps tdrd2, anticorps MGC85144, anticorps TDRD2, anticorps 2700091C21Rik, anticorps Tdrd2, anticorps tudor and KH domain containing, anticorps tudor and KH domain containing L homeolog, anticorps tudor and KH domain containing protein, anticorps Tdrkh, anticorps TDRKH, anticorps tdrkh.L, anticorps tdrkh

Sujet: 2700091C21Rik, Putative RNA binding protein, RGD1311196, RP11-98D18.8, TDRD2, TDRD7, Tdrkh, Tudor and KH domain containing, Tudor and KH domain-containing protein, tudor domain containing 2,TDRKH
Cellular localisation: Cytoplasm. Localized to cytosol and centrosome.

Poids moléculaire: 62.05kDa

ID gène: 11022, 144439

UniProt: Q9Y2W6