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E4F1 anticorps

E4F1 Reactivité: Humain IF, FACS Hôte: Souris Monoclonal unconjugated
N° du produit ABIN7126308
  • Antigène Voir toutes E4F1 Anticorps
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Reactivité
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 7
    • 3
    Souris
    Clonalité
    • 9
    • 1
    Monoclonal
    Conjugué
    • 10
    Cet anticorp E4F1 est non-conjugé
    Application
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificité
    E4F1 (E4F transcription factor 1), also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains 9 C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.
    Réactivité croisée (Details)
    Human
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human E4F1 protein
    Isotype
    IgG1
    Top Product
    Discover our top product E4F1 Anticorps primaire
  • Indications d'application

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, Jurkat or MCF7 cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Autre désignation
    E4F1 (E4F1 Produits)
    Synonymes
    anticorps e4f, anticorps MGC147041, anticorps E4F, anticorps Dnase1l2, anticorps zgc:114190, anticorps E4F transcription factor 1, anticorps E4F transcription factor 1 S homeolog, anticorps E4F1, anticorps e4f1, anticorps e4f1.S, anticorps E4f1
    Sujet
    E4F transcription factor 1, isoform CRA_b, P120E4F transcription factor, p50E4F, Putative E3 ubiquitin-protein ligase E4F1, RING type E3 ubiquitin transferase E4F1, Transcription factor E4F1,E4F1
    Cellular localisation: Nucleus.
    Poids moléculaire
    83kDa
    ID gène
    1877, 513268
    UniProt
    Q66K89
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