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POLE3 anticorps

POLE3 Reactivité: Humain IF, ELISA, IP, FACS, Coat Hôte: Souris Monoclonal unconjugated
N° du produit ABIN7126802
  • Antigène Voir toutes POLE3 Anticorps
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Reactivité
    • 39
    • 20
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 34
    • 5
    Souris
    Clonalité
    • 37
    • 2
    Monoclonal
    Conjugué
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp POLE3 est non-conjugé
    Application
    • 23
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Coating (Coat)
    Specificité
    DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex), which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodeling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array. In the presence of CHRAC, the nucleosomal ATPase ISWI catalyzes several ATP-dependent transitions of chromatin structure.
    Réactivité croisée (Details)
    Human. Predicted to react in Mouse, Rat and Xenopus.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human POLE3 protein
    Isotype
    IgG2a
    Top Product
    Discover our top product POLE3 Anticorps primaire
  • Indications d'application

    Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells),Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Autre désignation
    POLE3 (POLE3 Produits)
    Synonymes
    anticorps NCU04548.1, anticorps GB14966, anticorps zgc:73351, anticorps 1810034K18Rik, anticorps YBL1, anticorps CHARAC17, anticorps CHRAC17, anticorps p17, anticorps DNA polymerase epsilon 3, accessory subunit, anticorps polymerase (DNA directed), epsilon 3, accessory subunit, anticorps DNA polymerase epsilon, anticorps DNA polymerase epsilon p17 subunit, anticorps DNA polymerase epsilon subunit 3, anticorps polymerase (DNA directed), epsilon 3 (p17 subunit), anticorps POLE3, anticorps pole3, anticorps NCU04548, anticorps CpipJ_CPIJ008666, anticorps Bm1_04865, anticorps Bm1_07285, anticorps CTRG_00708, anticorps LOAG_09571, anticorps LOC726923, anticorps Pole3
    Sujet
    Arsenic transactivated protein, ASTP, CHRAC17, Chromatin accessibility complex 17 kDa protein, DNA polymerase II subunit 3, Histone fold protein CHRAC17, HuCHRAC17, Polymerase (DNA directed) epsilon 3 (POLE3), YBL1,POLE3 / CHRAC17
    Cellular localisation: Nucleus.
    Poids moléculaire
    16.86kDa
    ID gène
    54107, 108112
    UniProt
    Q9NRF9
    Pathways
    Réparation de l'ADN
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