Recombinant S100P anticorps (C-Term)

N° du produit ABIN7126919

Détail du produit anti-S100P anticorps

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Type d'anticorp: Recombinant Antibody

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp S100P est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment corresponding to C-terminal of human S100P protein

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human pancreatic adenocarcinoma, placenta or spleen tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur S100P

Antigène: S100P (S100 Calcium Binding Protein P (S100P))

Autre désignation: S100P (S100P Produits)

Synonymes: anticorps MIG9, anticorps S100P, anticorps S100p, anticorps S100 calcium binding protein P, anticorps S100 calcium binding protein B, anticorps S100 calcium binding protein P pseudogene, anticorps S100P, anticorps s100p, anticorps S100b, anticorps S100p, anticorps Gm40318

Sujet: Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P,S100P
Cellular localisation: Nucleus. Cytoplasm. Colocalizes with S100PBP in the nucleus.

Poids moléculaire: 10kDa

ID gène: 6286, 2962

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins