NOC4L anticorps
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- Antigène Tous les produits NOC4L
- NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NOC4L est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificité
- Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
- Réactivité croisée (Details)
- Human
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human NOC4L protein
- Isotype
- IgG1
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or 293T cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))
- Autre désignation
- NOC4L (NOC4L Produits)
- Synonymes
- anticorps NET49, anticorps NOC4, anticorps UTP19, anticorps NOC4L, anticorps AI326906, anticorps RGD1310661, anticorps net49, anticorps noc4, anticorps noc4lb, anticorps noc4la, anticorps NOC4 protein homolog, anticorps sb:cb534, anticorps wu:fb78g04, anticorps zgc:110429, anticorps nucleolar complex associated 4 homolog, anticorps NOC4 like, anticorps nucleolar complex associated 4 homolog S homeolog, anticorps nucleolar complex associated 4 homolog L homeolog, anticorps NOC4L, anticorps Noc4l, anticorps noc4l.S, anticorps noc4l.L, anticorps noc4l
- Sujet
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NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein,Nucleolar complex-associated protein 4-like protein (NOC4L)
Cellular localisation: Nucleus. - Poids moléculaire
- 58.4kDa
- ID gène
- 79050, 558536
- UniProt
- Q9BVI4
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