GTF2IRD2 anticorps
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- Antigène Voir toutes GTF2IRD2 Anticorps
- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GTF2IRD2 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificité
- The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human GTF2IRD2 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product GTF2IRD2 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or K562 cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
- Autre désignation
- GTF2IRD2 (GTF2IRD2 Produits)
- Synonymes
- anticorps FP630, anticorps GTF2IRD2 alpha, anticorps GTF2IRD2A, anticorps 1700012P16Rik, anticorps GTF2I repeat domain containing 2, anticorps GTF2IRD2, anticorps Gtf2ird2
- Sujet
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FP630, GTF2IRD2A, GTF2IRD2 alpha,GTF2IRD2
Cellular localisation: Nucleus. - Poids moléculaire
- 107kDa
- ID gène
- 84163, 647039
- UniProt
- Q86UP8
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