Recombinant MCAM anticorps
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- Antigène Voir toutes MCAM Anticorps
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MCAM est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA
- Réactivité croisée
- Humain
- Purification
- Affinity-chromatography
- Immunogène
- A synthesized peptide
- Clone
- 8A10
- Isotype
- IgG
- Top Product
- Discover our top product MCAM Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:30-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
- Autre désignation
- MCAM (MCAM Produits)
- Synonymes
- anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb
- Sujet
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Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Aliases: Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146, MCAM, MUC18
- UniProt
- P43121
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