Recombinant Histone H3.3 anticorps

N° du produit ABIN7127296

Détail du produit anti-Histone H3.3 anticorps

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H3.3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide

Clone: 4H2

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:50-1:500, IF:1:30-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Histone H3.3

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Autre désignation: H3F3A (H3F3A Produits)

Synonymes: anticorps H3.3A, anticorps H3F3, anticorps h3f3a, anticorps MGC52829, anticorps wu:fb58e10, anticorps zgc:56193, anticorps zgc:86731, anticorps H3-I, anticorps H3-II, anticorps H3-III, anticorps H3-IV, anticorps H3-V, anticorps H3-VI, anticorps H3-VII, anticorps H3-VIII, anticorps H3F3A, anticorps h3.3, anticorps h3.3a, anticorps CG5825, anticorps Dmel\\CG5825, anticorps H3.3, anticorps His-3.3A, anticorps His3.3, anticorps PH3, anticorps dH3.3A, anticorps H3 histone family member 3A, anticorps H3 histone, family 3A, anticorps H3 histone, family 3A L homeolog, anticorps H3 histone, family 3C, anticorps histone H3.3, anticorps histone cluster 1, H3a, anticorps Histone H3.3A, anticorps H3F3A, anticorps h3f3a.L, anticorps h3f3a, anticorps H3F3C, anticorps LOC475916, anticorps LOC480110, anticorps HIST1H3A, anticorps LOAG_05159, anticorps His3.3A, anticorps H3f3a

Sujet:

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B

UniProt: P84243