Recombinant Hepcidin anticorps

N° du produit ABIN7127534

Détail du produit anti-Hepcidin anticorps

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human HAMP

Clone: 4C5

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: HAMP (HAMP Produits)

Synonymes: anticorps HEPC, anticorps HFE2B, anticorps LEAP1, anticorps PLTR, anticorps Hepcidin, anticorps Hamp1, anticorps Hepc, anticorps Hepc1, anticorps HAMP, anticorps hepcidin, anticorps hamp1, anticorps hep1, anticorps hepcidin antimicrobial peptide, anticorps hepcidin-like, anticorps hepcidin-1, anticorps Ham percentage, anticorps HAMP, anticorps Hamp, anticorps hamp, anticorps LOC100135935, anticorps LOC106584587

Sujet:

Background: Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).

Aliases: Hepcidin, Liver-expressed antimicrobial peptide 1, LEAP-1, Putative liver tumor regressor, PLTR, Hepcidin-25, Hepc25, Hepcidin-20, Hepc20, HAMP, HEPC, LEAP1, UNQ487/PRO1003

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis