Recombinant KLF4 anticorps

N° du produit ABIN7127591

Détail du produit anti-KLF4 anticorps

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KLF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human KLF4

Clone: 3A1

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KLF4

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Autre désignation: KLF4 (KLF4 Produits)

Synonymes: anticorps EZF, anticorps GKLF, anticorps Gklf, anticorps Zie, anticorps KLF4, anticorps biklf, anticorps biklf-A, anticorps Kruppel like factor 4, anticorps Kruppel-like factor 4 (gut), anticorps Kruppel-like factor 4, anticorps Kruppel-like factor 4 (gut) L homeolog, anticorps KLF4, anticorps Klf4, anticorps klf4, anticorps klf4.L

Sujet:

Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Aliases: Krueppel-like factor 4 (Epithelial zinc finger protein EZF) (Gut-enriched krueppel-like factor), KLF4, EZF GKLF

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance