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Recombinant MGMT anticorps

MGMT Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Monoclonal 10G7 unconjugated Recombinant Antibody
N° du produit ABIN7127619
  • Antigène Voir toutes MGMT Anticorps
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 72
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 68
    • 11
    Lapin
    Clonalité
    • 62
    • 17
    Monoclonal
    Conjugué
    • 44
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp MGMT est non-conjugé
    Application
    • 54
    • 32
    • 21
    • 19
    • 13
    • 13
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human MGMT
    Clone
    10G7
    Isotype
    IgG
    Top Product
    Discover our top product MGMT Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Autre désignation
    MGMT (MGMT Produits)
    Synonymes
    anticorps AGT, anticorps AI267024, anticorps Agat, anticorps O-6-methylguanine-DNA methyltransferase, anticorps MGMT, anticorps Mgmt
    Sujet

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Aliases: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase), MGMT

    UniProt
    P16455
    Pathways
    Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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