Recombinant NUP153 anticorps

N° du produit ABIN7127649

Détail du produit anti-NUP153 anticorps

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NUP153 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Nup153

Clone: 8D4

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NUP153

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Autre désignation: NUP153 (NUP153 Produits)

Synonymes: anticorps CG4453, anticorps Dmel\\CG4453, anticorps NUP153, anticorps Nup 153, anticorps dNup153, anticorps dmNup153, anticorps nup153, anticorps NUCZINK, anticorps B130015D15Rik, anticorps C88147, anticorps HNUP153, anticorps N153, anticorps Nucleoporin 153kD, anticorps nucleoporin 153, anticorps nucleoporin 153kDa L homeolog, anticorps Nup153, anticorps NUP153, anticorps nup153.L

Sujet:

Background: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Aliases: Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153), NUP153

UniProt: P49790

Pathways: Protein targeting to Nucleus