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Recombinant PTBP1 anticorps

PTBP1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Monoclonal 8A1 unconjugated Recombinant Antibody
N° du produit ABIN7127781
  • Antigène Voir toutes PTBP1 Anticorps
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 53
    • 18
    • 16
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 7
    • 1
    Lapin
    Clonalité
    • 35
    • 18
    Monoclonal
    Conjugué
    • 31
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp PTBP1 est non-conjugé
    Application
    • 34
    • 19
    • 13
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human PTBP1
    Clone
    8A1
    Isotype
    IgG
    Top Product
    Discover our top product PTBP1 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    Autre désignation
    PTBP1 (PTBP1 Produits)
    Sujet

    Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).

    Aliases: Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB

    UniProt
    P26599
    Pathways
    Regulation of Muscle Cell Differentiation
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