Recombinant RPE65 anticorps

N° du produit ABIN7127798

Détail du produit anti-RPE65 anticorps

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPE65 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human RPE65

Clone: 7B10

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPE65

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Autre désignation: RPE65 (RPE65 Produits)

Synonymes: anticorps LCA2, anticorps RP20, anticorps mRPE65, anticorps rd12, anticorps sRPE65, anticorps 65kDa, anticorps A930029L06Rik, anticorps Mord1, anticorps DRPE65, anticorps RPE65, anticorps anon-WO0148162.1, anticorps anon-WO0148163.1, anticorps beta-diox, anticorps DmelCG9347, anticorps CG9347, anticorps MGC52887, anticorps MGC154296, anticorps MGC85437, anticorps rpe65, anticorps RPE56c, anticorps si:ch211-198n5.12, anticorps 13cIMH, anticorps RPE56b, anticorps rpepb, anticorps si:ch211-198n5.5, anticorps wu:fc74c09, anticorps zgc:110538, anticorps RPE56a, anticorps rpepa, anticorps zgc:73213, anticorps RPE65, retinoid isomerohydrolase, anticorps retinal pigment epithelium 65, anticorps neither inactivation nor afterpotential B, anticorps retinal pigment epithelium-specific protein 65kDa S homeolog, anticorps retinal pigment epithelium-specific protein 65kDa L homeolog, anticorps RPE65 homolog, anticorps retinal pigment epithelium-specific protein 65kDa, anticorps retinal pigment epithelium-specific protein 65c, anticorps retinal pigment epithelium-specific protein 65b, anticorps retinal pigment epithelium-specific protein 65a, anticorps RPE65, anticorps Rpe65, anticorps ninaB, anticorps rpe65.S, anticorps rpe65.L, anticorps rpe65, anticorps rpe65c, anticorps rpe65b, anticorps rpe65a

Sujet:

Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Aliases: Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Meso-zeaxanthin isomerase) (EC 5.3.3.-) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase), RPE65

UniProt: Q16518