Recombinant SKP2 anticorps
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- Antigène Voir toutes SKP2 Anticorps
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Type d'anticorp
- Recombinant Antibody
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SKP2 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- Affinity-chromatography
- Immunogène
- A synthesized peptide derived from human SKP2
- Clone
- 6D4
- Isotype
- IgG
- Top Product
- Discover our top product SKP2 Anticorps primaire
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anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 351-424) antibody
SKP2 Reactivité: Humain, Souris, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (C-Term) antibodySKP2 Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-100) antibodySKP2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 43-397) antibodySKP2 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reactivité: Humain ELISA, IF, FACS Hôte: Lapin Monoclonal 3C11 unconjugated Recombinant Antibody
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 156-185) antibodySKP2 Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB19860 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-130) antibodySKP2 Reactivité: Humain ELISA Hôte: Souris Monoclonal 6G9D10 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 Reactivité: Humain WB, PLA Hôte: Souris Polyclonal unconjugated
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- Indications d'application
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Autre désignation
- SKP2 (SKP2 Produits)
- Synonymes
- anticorps FBXL1, anticorps FBL1, anticorps FLB1, anticorps p45, anticorps RGD1562456, anticorps S-phase kinase-associated protein 2 (p45), anticorps S-phase kinase associated protein 2, anticorps Skp2, anticorps SKP2
- Sujet
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.
Aliases: S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2), SKP2, FBXL1
- UniProt
- Q13309
- Pathways
- Mitotic G1-G1/S Phases
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